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November 22nd 2025 Protocol Updates

November 22, 2025

November's Level 1, 2, 3 Protocol Updates

- We suggest ChatGPT 5.1 thinking (or Pro) for medical related questions, above all other models

- Dr Zolman gave a talk alongside Anne Boden, the Founder of Starling Bank at the Graduate Network in Marleybone showcasing his latest update to Longevity Level 1 (now 18 components), including specific ApoB targets. Level 1 are the most evidence-based, highest-impact interventions at the population level.

- A huge breakthrough in 'heavy Omega 3 and Omega 6' supplements has been achieved by Dr Zolman's colleague, making these molecules impossible to undergo oxidation chain reactions - and may resolve a fundamental ageing process, and are now taking pre-orders commercially available (No affiliation). The downside? $1000 a month currently due to economies of scale.

- pTau217 is a new Alzheimer's blood test you have to know about - and monitoring it when lowering ApoB to very low levels, may make lowering ApoB safer.

- A new type of hyaluronic acid filler may be completely free of the toxic compound BDDE (unlike Juvederm, Restylane) - one molecule responsible for migration and long-term reactions


- This is your personal reminder from Dr Zolman to get a personal trainer - sessions are often subsidised by the local government to be as low as $30/£25.