About Oliver

Go to www.oliverzolman.com and www.longevity.school to learn more about my Longevity Level 1, 2, 3 evidence-based clinical protocol.

 

Our Cambridge UK based research company is working to prove age reduction from age 80 to 60 (25% mean organ age reduction with low organ age SD) by 2030, in all 78 organs.

 

1) I have created the 500+ Zolman Clocks to measure biological age in all 78 organ types across both genders, comprised of over 500 sub-clocks (multiple clocks per organ) to prove reversal of aging and prove n=1 LEV (longevity escape velocity) using my N=1 LEV equation.

 

2) I have written the Zolman Biological Age Marker (Z-BAM) criteria, with evergreen peer-review, 15 statistical criteria that markers must meet a minimum set of to be statistically and clinically valid, with no close comparison of such objective criteria made before to critically appraise biological age markers of any type (imaging, device or biosample based)

 

3) I created the Longevity Level 123 protocol to measure and reverse aging in all 78 organs using the most statistically rationale evidence based medicine (EBM) approach. This involves writing hundreds of novel experimental clinical guidelines covering every experimental longevity test and therapy, built on international gold-standard EBM principles such as AGREE2, IPDAS, N=1 CONSORT, GRADE, Cochrane Handbook of systematic reviews, NICE manual, etc. I have also extended beyond these gold-standards with my own standards for informed consent.

 

Level 123 protocol is designed using systems thinking to be unsurpassably systematic in every possible evidence based factor that can contribute to unwanted clinical or biomarker (imaging, device, biosample) outcomes

 

Level 1 = Proven to raise mean lifespan by 2+ years in 50%+ of people and stack their effects: 6 components: CRON, AHEI-2010 diet, Exercise, BMI, Alcohol, Smoking
 

Level 2 = Non-age related: 13 categories of non-age related causes of unwanted clinical outcomes
 

Level 3 = Measure 500+ Zolman Clocks, other clocks, 78 organ ages, Level 3 tests and therapies experimental clinical guidelines

 

4) I created Longevity School to teach Longevity 123 protocol and how to measure the 78 organ clocks at research grade standard. This allows clinicians and innovators to become their own rejuvenation research groups by using gold-standard markers with gold-standard methodology, and see which organs or markers they can rejuvenate with on label, off label or unlicensed therapies.

 

Longevity School is an online platform with native mobile apps, desktop apps, video content that adheres to Medical Education gold-standards, evergreen peer-review and conflict of interest statements. Longevity School provides certification and revalidation in Longevity Escape Velocity Medicine (LEVMED) Speciality Training, first published in the peer-reviewed PubMed listed journal Rejuvenation Research February edition in 2018 and presented at the 2018 the Undoing Aging Conference.

 

5) I created the field of competitive longevity, publishing the first Rejuvenation Leaderboards and using a rationale and evidence based points system based on the 500+ Zolman Component Clocks to rank individuals. I further expanded this concept to sub-leaderboards for specific organ rejuvenation.

 

6) I have also created many multi-organ clocks that provide a systemic view of aging processes that will affect many organs, these also need to be reversed.

 

7) I have created the first organ age heatmaps which show biological age heatmaps within organs, showing which parts of one's individual organs are aging fastest and causing the overall organ to be older.

 

8) I actively call out pseudomedicine, pseudo-aging tests, pseudo aging therapies, sub-par practice and objectively irrational thinking using evidence based medicine principles and peer-reviewed references to back up my claims. This includes the concept of 'no guideline --> no experimental test or therapy'.

 

9) I have written the first experimental clinical guidelines and pharmacokinetic pharmacodynamic translational models for all wild type mouse lifespan studies interventions, e.g. Rapamycin, Alfatradiol, NGDA, AAV/CMV HTERT/Follistatin/klotho etc (50+). I have ranked every wild type mouse lifespan study by effect size on maximal lifespan and this is a core part of longevity school and level 3 therapy strategy.

 

His clientele include Bryan Johnson, founder of Braintree-Venmo (sold to Paypal for $800M), Kernel and OS Fund, and with Oliver created Project Blueprint, documenting his work with Oliver to maximally reverse the quantified biological age of all of his organs using the 500+ Zolman Clocks and Level 123 protocol. Bryan and Oliver's parents are the first people to go through the Longevity Level 123 protocol, quantify the biological age of all 78 organs using Zolman Clocks and maximally reverse them using Level 123 therapies experimental clinical guidelines.

 

Qualifications

 

Oliver earned his M.B.B.S. from King's College London, England (equivalent to the US M.D.)

 

First Class Honours BSc in Regenerative Medicine, Innovation Technology & Biology of Aging.

 

Visiting Fellowship in Evidence Based Medicine, at the University of Sydney

 

Cambridge University Judge Business School Accelerator Program

 

Cambridge University Medical Education Masters to be started in 2023